Pharmacological treatment for unipolar psychotic depression

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Pharmacological treatment for unipolar psychotic depression: Systematic review and meta-analysis.

BACKGROUND The optimal pharmacological treatment of unipolar psychotic depression is uncertain. AIMS To compare the clinical effectiveness of pharmacological treatments for patients with unipolar psychotic depression. METHOD Systematic review and meta-analysis of randomised controlled trials. RESULTS Ten trials were included in the review. We found no evidence that the combination of an a...

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Treatment of unipolar psychotic depression: an open study of lithium addition in refractory psychotic depression.

Objective: This study was designed to compare the efficacy of three two-phase pharmacological treatment strategies for inpatients with DSM-IV-TR major depressive disorder with psychotic features. Method: During phase I, 122 patients participated in a 7 week double-blind eight center study comparing imipramine (dose adjusted to target plasma levels of 200300 ng/ml), venlafaxine (maximum 375 mg/d...

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Pharmacological management of unipolar depression.

OBJECTIVE To be used in conjunction with 'Psychological management of unipolar depression' [Lampe et al. Acta Psychiatr Scand 2013;127(Suppl. 443):24-37] and 'Lifestyle management of unipolar depression' [Berk et al. Acta Psychiatr Scand 2013;127(Suppl. 443):38-54]. To provide clinically relevant recommendations for the use of pharmacological treatments in depression derived from a literature r...

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Drug treatment for psychotic depression.

I read the review article by Wijkstra et al (2006) with much interest as I found the results in the abstract quite striking. However, I wish to raise a few points about the methodology and description of results. First, the authors have concluded from two studies by Bruijn et al (1996) and van den Broek et al (2004) that tricyclic antidepressants (TCAs) are more efficacious than non-TCAs in tre...

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Drug treatment for psychotic depression

I read the review article by Wijkstra et al (2006) with much interest as I found the results in the abstract quite striking. However, I wish to raise a few points about the methodology and description of results. First, the authors have concluded from two studies by Bruijn et al (1996) and van den Broek et al (2004) that tricyclic antidepressants (TCAs) are more efficacious than non-TCAs in tre...

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ژورنال

عنوان ژورنال: British Journal of Psychiatry

سال: 2006

ISSN: 0007-1250,1472-1465

DOI: 10.1192/bjp.bp.105.010470